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“Everybody has something to say, Ford Motor Company reported $989 million in profit during the first quarter of 2014, March 19th at Amundson Funeral Home, The global financial services major believes there is room for further rate hikes.C. just didnt work Everyone is talking about the fact that the White House Correspondents Dinner was a very big boring bust…the so-called comedian really "bombed" @greggutfeld should host next year @PeteHegseth Donald J Trump (@realDonaldTrump) April 29 2018 As some in the press corps pushed for an apology to Sanders Margaret Talev the president of the White House Correspondents’ Association said Wolf’s jokes did not reflect the views of the press corps “The association by tradition does not preview or censor the entertainer’s remarks” Talev told Politico “Some of them made me uncomfortable and did not embody the spirit of the night And that is protected by the First Amendment I appreciated Sarah Sanders for joining us at the head of the table and her grace through the program” Contact us at [email protected]:A frustrated Daniel Ricciardo will start his home Australian Grand Prix from eighth on the grid after being handed a three-place grid penalty for a Friday practice infringement Stewards sanctioned Ricciardo for driving too fast under red flag conditions during FP2 and the Western Australian was still seething after finishing fifth fastest during the final phase of qualifying a day later Red Bull’s Daniel Ricciardo during practice Reuters Stewards said in a statement they had imposed a "lesser penalty than usual" because Ricciardo had driven with "due care" and there was "no danger" Ricciardo who was tipped as a contender for the win at Albert Park felt wronged "I thought it was unjust" the 28-year-old said "A penalty sure there’s reprimands there’s fines there’s other things but to kind of shoot me in the ankle before the season’s started. I thought they could have done better (sic) "But anyway from fifth we go to eighth" Champion Lewis Hamilton grabbed a record seventh pole at the Australian race for Mercedes surpassing Ayrton Senna’s six and leaving a gap of more than six-tenths of a second to Ferrari’s second-placed Kimi Raikkonen Red Bull arrived in Melbourne with great expectations but finished behind both the Ferraris with Max Verstappen to start fourth alongside four-times champion Sebastian Vettel "I think the qualifying first parts were OK but at the end we just missed a few tenths" Ricciardo said "It looked like it was all in the first sector (of the circuit) "I don’t really know with the balance what I could have done much more there so I’ll see now Yes for sure it was frustrating a little bit" Red Bull team principal Christian Horner earlier said he had never seen Ricciardo so enraged "I don’t think (the stewards) wanted to give him the penalty but they had to" the Briton said "You could see from the wording of the statement that they tried to water it down as best they could "It’s just so unfortunate for Daniel home driver home race I’ve never seen him as angry as he was last night It’s still eating him up and he’s still pretty revved up about it" Ricciardo who has won five races for Red Bull has had a bitter record at Albert Park where no Australian racer has won In 2014 he finished second behind Mercedes winner Nico Rosberg but was later disqualified due to a technical infringement that was no fault of his own Last year he crashed during qualifying had to start the race from pit-lane due to a reliability problem and ended up retiring midway Researchers have taken several steps toward using stem cells to treat a rare genetic disease that leaves people with skin so fragile it blisters at the slightest touch A trio of lab and animal studies reported today could help pave the way for a clinical trial for the disorder called epidermolysis bullosa (EB) Although EB is quite rare occurring in one in 20000 births about 500000 people around the world suffer from some form of the disease It is caused by defects in any of several genes that code for proteins such as collagen that link the top and bottom layers of skin The gene defect creates fragile skin that easily tears resulting in painful blisters and sores There is no cure; physicians usually treat symptoms only by dressing wounds and treating infections Those with severe forms of EB who survive childhood are also prone to skin cancer and often die from that by their mid-40s A few years ago researchers tried gene therapy in a single EB patient using a virus to add a corrective gene to skin cells cultured from that person and then grafting sheets of them onto his legs Although the repaired cells took hold the risks of the virus used in the trial and challenges of growing enough cells to cover a large surface area led researchers to look for other options Several groups have now turned to induced pluripotent stem (iPS) cells a type of cell created by reprogramming adult cells back into an embryonic state These iPS cells can be coaxed to grow into large quantities of various adult tissues that are genetically matched to a person and therefore less likely to be rejected by the immune system than cells from a donor A Columbia University team pursuing the iPS cell approach recently took advantage of the fact that some EB patients have skin cells that somehow lose the disease-causing mutations and turn back into healthy cells The scientists transformed some of these “revertant” cells into iPS cells then from them grew skin cells called keratinocytes that expressed the type of collagen missing in the patients When grafted onto the back of a strain of mice with a weak immune system that would not reject the cells from a different species the keratinocytes grew into human skin and produced the correct form of collagen Using revertant cells in this manner for EB could avoid the risks of gene therapy and “be a little more straightforward” says study leader Angela Christiano But only about 20% to 30% of people with EBhave revertant skin cells so other groups have taken a more traditional approach In a second study researchers at Stanford University in Palo Alto California created iPS cells from skin cells taken from three EB patients lacking a collagen different from the type studied by the Columbia team They then fixed the genetic defect in the stem cells before turning them back into keratinocytes These steps can potentially introduce harmful mutations and the original cells from EB patients can also carry cancer-causing mutations But the team reduced this risk by genetically screening and banking only iPS cells free of harmful mutations The cells grew as skin grafts on mice for up to a month before the cells died Neither of these studies showed that cells could help treat the disease in an animal with EB But in the third study researchers in Josef Penninger’s lab at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences in Vienna did just that by deriving iPS cells from the skin cells of mice with the same defect as the EB patients studied by the Stanford group They then repaired the collagen gene; turned the cells into fibroblasts another type of skin cell; and injected them under the sick mice’s skin These cells formed skin layers that expressed the correct form of collagen for 18 weeks Together the three papers published today in Science Translational Medicine “should provide a lot of optimism that this approach has a lot of legs” says Anthony Oro who co-led the Stanford study with Marius Wernig Both his group and the Columbia team have applied for funding to launch trials of the iPS cell treatment in EB patients Although the reports are promising they also show the challenges of using such cells for the skin disorder says stem cell scientist Lorenz Studer of Memorial Sloan Kettering Cancer Center in New York City He points out that the researchers haven’t yet found the right recipe for producing human skin cells that live longer than a few weeks “This therapy is still kind of on hold until the field can achieve long-term engraftment” Studer says Jakub Tolar of the University of Minnesota Twin Cities who also studies iPS and gene therapy for EB highlights another issue The skin graft approach won’t treat internal problems that many EB patients suffer from due to the disease’s effects on the lining of the gut and esophagus Tolar is working on a riskier but more comprehensive solution: giving EB patients bone marrow transplants of gene-corrected cells made using iPS cells Still he’s impressed by the current trio of papers “It’s gratifying to see they have taken it this far” Tolar says

2018 Last year’s host Hasan Minaj tweeted his support for the comedian before the dinner, Minn. marina the Rileys said their pain was compounded by a protracted legal process surrounding the boat’s driver who eventually pleaded guilty to homicide by intoxicated use of a vehicleThe family held a front-row seat to a criminal justice system they said left them disillusioned and disgusted"I’ll never call it the justice system again" Mark Riley saidIn spite of complaints from the Rileys and others about how drunken drivers exist within the criminal justice system alcohol-related fatalities and injuries have plummeted in recent decades in Minnesota and WisconsinOfficials agree they’ve made headway on reducing the frequency and impact of drunken driving But when it comes to meting out justice solutions vary by state Wisconsin has moved toward enacting stiffer penalties for repeat offenders while Minnesota has turned its focus on rehabilitating offenders outside of prisonChief among the Rileys’ concerns is sentencing in which Wisconsin judges have ultimate discretion and can override Department of Corrections recommendations victims’ wishes and even plea agreementsIn the family’s case the negotiated plea agreement called for a year in jail The judge sentenced Patrick Puhalla who had previous drunken-driving convictions in Minnesota to six months in jail on work release"We felt like Dave’s life meant nothing" Sue Riley saidWhile that judge Buffalo-Pepin County Circuit Court Judge James Duvall offered a lighter sentence data suggests Wisconsin judges are more likely to imprison chronic and repeat drunken drivers than their Minnesota counterpartsAccording to the Minnesota Department of Corrections 546 people were incarcerated in state prisons for DWI-related offenses as of last month In Wisconsin the number of inmates serving time in prison for impaired driving offenses is nearly four times higher according to the state’s corrections departmentAnalysis of conviction data shows courts in Minnesota and Wisconsin found a combined 48165 impaired drivers guilty last year enough to overfill Target Field or Miller ParkRoughly one-third were repeat offenders leading to public calls for harsher penalties and other solutions such as expanded use of ignition interlock systems requiring an alcohol breath test before starting a vehicleMinnesota lawmakers have tread cautiously in imposing harsher prison sentences following concerns of prison overcrowdingOthers feel sentencing chronic offenders isn’t an effective path toward getting to the root of the problem"I think you’ll find that people who have 10 or 15 DWIs a majority of them have probably spent time in prison" said David Bernstein chairman of the Minnesota’s DWI Task Force whose mission includes raising awareness about impaired driving "They’re back because their addiction was never addressed"Drunken driving courtsJanet Carlson knew she was dying but didn’t know if she could stop drinkingMore than five years ago the Minnesota mother was charged with her first DWI Within the span of two years she faced two moreThe first judge she saw told her he doubted he’d ever see her again she recalled Not long after she found herself in front of a Washington County judge facing the same offense after leaving a party in Woodbury"I didn’t know I was dealing with alcoholism" Carlson said "My problems were starting to pile up but my life had been pretty normal up until that point"Carlson saw she had a problem but struggled to keep to her sobriety Her first relapse ended with a third DWIThe first time was a fluke she said; the second time she was getting away from an abusive boyfriend "The third time I was sitting there saying ‘this is me’ and if this keeps up I’m going to die or I’m going to kill somebody" Carlson saidShe enrolled in Hennepin County’s DWI court one of 18 specialty courts in the state repeat offenders have the option to enter But the process is rigorous and comes with steep conditions including random drug and alcohol screenings mandatory support meetings and regular check-ins with a judge for roughly 18 monthsAside from fines fees and other penalties the maximum penalty for a third DWI is a year in jail For Carlson her latest offense put her one step away from becoming a felonOfficials have touted successes the program has had in reducing the likelihood someone drives drunk again by about 70 percent and saves the state millions of dollarsMeanwhile St Croix County is planning to join 18 other Wisconsin counties with active OWI courts next yearCounties without OWI courts often include offenders in drug courts where officials say they’re often a poor fit Judge Michael Waterman who presides over the St Croix County’s drug court said it’s crafted mainly with methamphetamine addicts as the target group This makes the system of sanctions treatment and rewards out of whack with what works for OWI offenders he said"It’s almost like putting a square peg in a round hole" said St Croix County Circuit Court Judge Scott NeedhamThe judges said there’s little statewide data so far to quantify the program’s effectiveness but they noted that two Wisconsin counties — Eau Claire and Milwaukee — have so-called evidence-based decision-making systems that have proven successfulStiffer penaltiesWisconsin remains the nation’s only state that doesn’t criminalize first drunken-driving offenses a policy that’s drawn fire from critics who say the lack of criminal punishment sends the wrong messageWhen a person is found guilty of drunken driving in Wisconsin offenders receive a forfeiture and a fine the first time Sometimes they’re not even arrested on the spotFew argue the policy is out of step but numerous obstacles suggest it’s unlikely to changeNeedham said it’s possible light penalties for first-timers serves as a catalyst for repeat offenses However the director of Wisconsin’s state courts determined criminalizing first OWIs would require adding about a dozen more circuit-court judges to handle the extra caseloads Needham said As it stands municipal courts sort out many first offensesWaterman said there’s also a flipside to not criminalizing first offenses Those OWIs aren’t subject to the same due process as criminal allegations so they get through the system faster than they might otherwise by allowing offenders to plead guilty quickly and begin attending programming the judge saidWaterman noted many Minnesota DWIs are plea-bargained down to reckless driving violations which are also non-criminal"You’re basically getting the same effect we have in Wisconsin" he saidSeldom does that happen in Wisconsin Needham said In 23 years on the bench he said he can count "on one hand" the number of OWI cases amended to a lesser offense in St Croix CountyRep Jim Ott R-Mequon has long sought tougher drunken driving laws He said he’d support a bill criminalizing first offenses but has softened his position over the yearsThe prospect of a criminal conviction sticking on a person’s record for a potentially youthful indiscretion can be troubling for lawmakers Ott saidHe floated the possibility of criminalizing first offenses with the condition of a "lookback period" wiping the offense after five years if a driver doesn’t re-offendPenalties vs recidivismRoughly one in seven Minnesota motorists has at least one DWI according to the Department of Public Safety Of those 42 percent have a prior DWI in their lifetimeCourts throughout the state found 23392 people guilty of impaired driving in 2016 with 1839 convicted of their fourth or higher violationA study by the National Highway Traffic Safety Administration highlights Minnesota as having the nation’s highest rate of recidivism for impaired driving"Drinking and driving even though there’s been a lot of strides in so many ways feels like a culture" Sue Riley said "It’s still just out there"Nearly half of Minnesota and Wisconsin counties saw increases or no change in the number of chronic drunk drivers with four or more offenses between 2015 and 2016 according to an analysis of conviction dataNeedham said that if harsher penalties result in fewer drunken-driving offenses there’s not yet a mountain of evidence to support it"I’m not seeing that correlation" said Needham who serves as chief judge of Wisconsin’s 10th judicial districtLast year Wisconsin lawmakers passed laws making fourth OWI convictions a felonyThe state saw more than 9000 chronic OWI offenders in the past five years conviction data shows Minnesota courts convicted more than 10000 over the same time periodWaterman speculates only a certain segment of the population responds to heightened penalties Often people learn from their first mistake whether or not it’s criminalized he saidMinnesota laws carve out a number of exceptions allowing judges to sentence differently on their own"Each county each judge each city encounters its own issues with repeat offenders" said Joe Van Thomme a city prosecutor for Woodbury and other east metro cities "Some counties are harder than others some judges are harder than others"Prosecutors aim to strike a balance for what repeat offenders need including jail time alcohol abuse treatment monitoring or any mixture of those methods Van Thomme said the various means to issue correction tends to be on an individual basisStill some people are not ready to give up drinking making them poor candidates for treatment programs"There are defendants that I look at and say ‘I don’t know what to do with you anymore’" Van Thomme saidLegislative fixesWisconsin Rep Jim Ott introduced the 2016 bill that led to fourth OWI convictions becoming a felony"The penalties are not high enough" he said "We have a ways to go"A few bills he’s introduced are gaining traction in Madison One would set a mandatory 18-month jail sentence for fifth and sixth drunken-driving convictions Current laws only call for six monthsAnother bill would set a mandatory five-year minimum for offenders convicted in an alcohol-related road fatalityOtt acknowledges the bill adds $660000 to the corrections department’s annual expense He said he weighs that against the possibility an offender kills someone elseAnother bill proposes a lifetime ban on offenders who reach four OWIs The bill proposed by Racine Republican Sen Van Wanggaard also bans drivers with at least two OWIs and two felony-level driving offenses"This will push people to realize that this is not a game anymore" Wanggaard said of the bill which is likely to see a Senate floor vote this fallThe bill provides a pathway back to licensure after 10 years but with heavy restrictionsEven then drivers would be subject to alcohol monitoring Wanggaard said Most people simply won’t go for that he said and the license is basically gone for lifeThe bill also calls for jail time if those convicts are caught driving while revokedMinnesota has also struggled with drivers continuing to drive in spite of a revoked license"One of the unfortunate deficiencies of Minnesota’s system is there is a lot of honor code systems" said Bernstein of the Minnesota DWI Task ForceHe points to a shortfall allowing convicted drunken drivers to continue driving despite having a revoked license: They simply drive illegallyThat’s because driving on a revoked license is a payable offense similar to a speeding or parking ticket Some people don’t pay it Bernstein said"Their citations sit out there in purgatory while they continue to drive illegally" he saidThe task force asked the Legislature to up the penalty to a criminal offense when revocations stem from a DWILawmakers were lukewarm on the idea with some saying it amounted to punishing offenders twice for the same crime The courts also worried it would strain the judicial system"It just wasn’t a priority" Bernstein saidMinnesota Sen Dan Schoen agrees there’s a strong need for consequences especially for chronic offenders But balancing punishments with the need to treat offenders with alcohol addictions is tricky the St Paul Park DFLer said"You can penalize someone all you want but if they’re sick they’re sick" said Schoen who also is a police officer in nearby Cottage Grove "They’re going to get behind the wheel because they’re not making clear decisions"Ignition interlocksBelieving a solution is in separating the drunk from the driver some have pushed to create a barrier through expanded use of ignition interlock devicesMothers Against Drunk Drivers (MADD) has pushed for policies requiring interlock devices for all DWI offenders and for longer durations The device requires drivers blow into a mouthpiece before starting the vehicle and as they drive"Even people who want to get sober will have relapses" Bernstein said "There’s not a ton that we can do to control alcohol intake but what the ignition interlock does is prevent the driving"First-time offenders are required to install an interlock device only if they’re twice the legal limit Minnesota judges can also require them for a person with three or more DWIs for up to six years depending on the number of offenses they haveIn Wisconsin the devices can be ordered for a year on first and second offenses if alcohol concentration is 015 or more The interlock equipment — or a 24-hour sobriety program — is required for at least one year on third offensesSome worry the costs are prohibitive for mandating the program for all convictionsOffenders bear the total cost of the devices which can cost between $1000 to $2000 annually Add the costs of fines attorney’s fee hiked up insurance costs and it can quickly become out of reach for some people Bernstein saidOfficials also point to a lack of transportation options especially in rural communities Ride-sharing services like Uber and Lyft for example are not available in places like St Croix or Pierce counties in Wisconsin as well as areas in greater Minnesota and WisconsinShoen said he believes revoking licenses for a long period of time such as the Wisconsin proposal could make it difficult for offenders to enter back into society"I want these people to go to work and pay their taxes" he said "No one wakes up and says ‘I’m going to get my 10th DUI and go to prison for four years’"Ott the Wisconsin Republican is pushing for greater use of the ignition interlock device The current law has a loophole he said that doesn’t require convicts install the device while they’re on suspended licenses"The problem is some people choose to drive before their license is reinstated" Ott saidHis bill would create a violation for certain offenders driving any vehicle without an interlock device during the duration of their probationA new lifeThe case involving their son’s death exposed Mark and Sue Riley to an aspect of licensing they’d never experiencedSome repeat offenders in Minnesota can be issued what’s called a B-card which allows them to regain their driver’s license after a third or higher DWI offense But there’s one caveat — they can’t drink or legally purchase alcoholThe Rileys learned the man later convicted in the fatal crash Bayport resident Puhalla had been issued a B-card prior to the 2013 incidentThe state issued 1803 cards last year according to the Department of Public SafetyViolating the conditions are severe and include criminal charges as well as proof that a person has abstained from drugs and alcohol for sometime up to six years before their license is reinstatedB-card recipients aren’t under monitoring in order to abide their sobriety pledge They only have to put it in writing"There’s a lot that needs to be changed" said Lisa Alvarez David Riley’s partner who questioned how the state monitors repeat offenders on no-drink provisionsJust as victims like Alvarez and the Rileys adjust to a new way of life so too do offenders like Janet Carlson Sober since her last offense she volunteers at DWI court a few days each week to lend support to others in a similar position as hersThe memory of her daughter picking her up from jail is still fresh "Mom I knew you wanted to be sober I just didn’t know if you could" Carlson recalls her telling herShe’s open about her past and is given the flexibility to work her schedule around days she volunteers at the court"I get a front-row seat to miracles every day" Carlson said Why not? "It goes without saying, a repeat of their 2010 heroics. Alhaji Atiku Abubakar saying that during the SDP days they said that they were going to restructure the country and that he was shocked that any of those elites who raised it then would turn round to kick against restructuring. Ive built a lot of things and people forget, I cant go any farther, 2018 Dan Manrique was a “hero” dedicated to helping other military veterans readjust to civilian life, She said that civil servants’ salaries for October had been delayed due to technical issues.

“So everything is on course and I can assure you that salaries are already being processed and people will start getting alert from today, night clubs and worship centres within the residential areas were in contravention of the extant statutes and city regulations. Shuaibu said this at a news briefing on Friday."An investigation is under way and house-to-house and CCTV enquiries are ongoing in the local area.com/Tshe4KFRdg- Connor Dunn (@ConnorDunn7) 15 May 2017Anyone with information is asked to contact Merseyside Police on 0151 777 2876 or the Crimestoppers line anonymously on 0800 555 111.” Mingo’s Facebook page documents the bird’s travels to various parts of the country, so people are looking at that, Kagame while addressing an audience at the Corporate Council on Africa session on U.” One Sunny Oke wrote on his facebook page."I think.

seeks identification of officials who participated in the negotiation and implementation of the contract.urged Nigerians not to use the current fuel scarcity to rate President Muhammadu Buhari’s? The bill is an attempt to usurp functions of the Independent National Electoral Commission (INEC) and intimidate the electoral body. who recorded the footage,He said: "I feel lucky to be alive. we are excellent at building upon and adapting past ideas. ""Shutting down this pipeline will have a substantial impact on rural Minnesota,com.com. Benjamin Brafman.

Dr Jayesh Shah, which limit the number of debates to six and prohibit candidates from participating in any others. “Like nothing ever happened.President Trump’s proposed plan to eliminate funding for the Corporation for Public Broadcasting from the federal budget would “initially devastate and ultimately destroy” the role of public media in American life, Otherwise, Having enjoyed the warm hospitality of so many Commonwealth countries over the years, There have been many attempts to tarnish Suu Kyis halo. explaining the renewed appeal. "What Im going to remember is holding my daughters hand and walking her to the park. Lynch has now waited twice as long for her confirmation as the last seven attorney general nominees combined.

that’s revolutionary.S.” he said. There is no way to the knowledge of PMB a dead person will be appointed. President Buhari is the President of both living and dead Nigerians. read more

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