New Smart Material Bends Under Internal Heat Source

first_img A team of scientists from CETIM CERMAT and the Laboratoire de Physique et de Mécanique Textiles (LPMT), both in Mulhouse, France, have been working on the active structure for the past few years. In a recent study published in Smart Materials and Structures, they present the material called CBCM (controlled behavior composite material), which can bend when heated.“The main advantage of the CBCM is that the entire structure is active, compared to classical actuators used in this kind of structures, such as shape memory alloys (SMA) or piezoelectric materials, so there is no problem of junction and connection between the actuator and the structure,” coauthor Gildas L’Hostis of LPMT told PhysOrg.com. “Moreover, the load that can carry the structure is much greater than the one carried by an SMA or piezoelectric material because the performances are not as limited by the rigidity of the composite structure. A third advantage is the simplicity of use – directly on DC current with a variator.”The CBCM consists of thin laminate plates, inside of which are highly conductive carbon yarns that are connected to a generator and serve as the internal heating source. When the power is turned on, the current circulates in the carbon yarns and the temperature rises in the plates. The increased temperature causes the plates to bend, and the deformation can be controlled by controlling the amount of current. The researchers experimented with two kinds of plates: “single effect” plates that can bend in one direction, and “double effect” plates that can bend in two directions. In the thin single effect plates, the temperature reached 57°C (135°F) and the structure deflected up to 15 mm. In the double effect plates (which consist of a conductive layer on one side and insulating layer on the other), the temperature reached 70°C (158°F) on the conductive side and 42°C (108°F) on the insulated side, and deflected up to 3.7 mm. While the single effect plates could deflect more, the double effect plates could lift a heavier load.The scientists also discussed incorporating a control system into the material. By adding temperature and strain sensors to the CBCM, such a system could detect variations in its background and then adapt to the new context. To demonstrate the new material, the researchers built a prototype of a 4-mm-thick retractable aerodynamic flap that could be used on cars for stabilization at high speeds. Unlike the existing flap, which has three joints and is moved with a jack, the smart material structure could move simply due to its thermomechanical properties.With its advantages over other actuators and moving components, the CBCM smart material could be useful for a variety of applications. However, more research is needed to overcome some difficulties, which the scientists highlighted in their study. For instance, future research could include testing the rigidity of the plates and minimizing local overheating, possibly with the use of carbon nanotubes. “The CBCM has already been used to manufacture an active binder for pipes,” said coauthor Karine Buet-Gautier of LPMT. “Today, some other active connectors are under study.”More information: Drobez, H.; L’Hostis, G.; Buet Gautier, K; Laurent, F.; and Durand, B. “A new active composite.” Smart Materials and Structures 18 (2009) 205020 (7pp).Copyright 2009 PhysOrg.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed in whole or part without the express written permission of PhysOrg.com. (PhysOrg.com) — Scientists have developed a new smart material that can bend under the influence of an internal heat source. The material could be used as an aerodynamic flap in cars, in order to stabilize the vehicles at high speeds. Because the entire structure actively bends, the material could have advantages over actuators that need to be externally fixed to a structure. A prototype of an aerodynamic flap made of the new smart material. The smart material consists of thin plates containing carbon yarns that can carry a current, which heats and bends the material. Image credit: H. Drobez, et al. Citation: New Smart Material Bends Under Internal Heat Source (2009, February 6) retrieved 18 August 2019 from https://phys.org/news/2009-02-smart-material-internal-source.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Researchers use GPS data to model effects of tidal loads on Earth’s surface Explore furtherlast_img read more

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Chemical snapshot Murchison meteorite reveals diversity of early Solar System

first_img The Murchison meteorite, a carbonaceous chondrite, fell near Murchison in Victoria in Australia in 1969, and is thought to be extremely ancient, possibly even older than the Sun, at 4.65 billion years old. It probably passed through the primordial clouds in the early Solar System, where it would have collected organic compounds. It was retrieved soon after it landed, which meant there was minimal chance of contamination, and it has been studied by scientists hoping the meteorite would yield clues about the possible origins of life on Earth. Leader of the research team, Dr Philippe Schmitt-Kopplin, said the meteorite was like a kind of fossil, and when you try to understand it, you are essentially looking back in time. Dr Schmitt-Kopplin, from the Helmholtz Centre Munich, in Germany, said he was really excited and amazed at the complexity they found. The meteorite has been investigated many times before, but earlier studies used gas chromatography and mass spectrometry and looked for specific compounds such as amino acids. The current study is the first non-targeted examination of the meteorite, and used high resolution technology such as NMR and ultra-high resolution mass spectrometry. The analysis took a few milligrams of crushed rock from the meteorite’s core, and then extracted the organic compounds with solvents.Their approach is based on metabolomics, which Schmitt-Kopplin and his team uses to analyze metabolites in body fluids. The technique attempts to find as many metabolites as possible, and they used the same system on the meteorite. Specifically, the new technique is known as the Fourier transform ion cyclotron resonance/mass spectrometry (FTICR/MS), which enables the scientists to weigh ionized molecules with the accuracy of the mass of an electron.The resolution of the analysis and the number of signals found makes the study record-breaking. Previous investigations were all targeted and used older technologies, and so the diversity was never discovered before. The results of the analysis identified about 14,000 different molecules in the meteorite, which can be combined in millions of different organic compounds. Schmitt-Kopplin said their calculations and interpolation were “very conservative”. Their findings show the nascent Solar System probably had more molecular diversity than present-day Earth.The results of the study appear in the Proceedings of the National Academy of Sciences (PNAS) journal. More information: High molecular diversity of extraterrestrial organic matter in Murchison meteorite revealed 40 years after its fall, Philippe Schmitt-Kopplin et al., PNAS February 16, 2010 vol. 107 no. 7 2763-2768, doi: 10.1073/pnas.0912157107 Murchison meteorite at the The National Museum of Natural History (Washington) © 2010 PhysOrg.com One-of-a-kind meteorite unveiled This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. (PhysOrg.com) — New studies of a meteorite that crashed to Earth four decades ago have found it probably contains millions of organic compounds. The findings shed light on the molecular complexity that existed at or just after the birth of the Solar System. Explore further Citation: Chemical snapshot: Murchison meteorite reveals diversity of early Solar System (2010, February 17) retrieved 18 August 2019 from https://phys.org/news/2010-02-chemical-snapshot-murchison-meteorite-reveals.htmllast_img read more

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Panasonic steps up 3D camera tech for virtual world tours

first_img Explore further Panasonic Develops World’s First 3D Full HD Plasma Theater System More information: ex-blog.panasonic.co.jp/ch_pan … h10/review03337.html (Phys.org)—If you can’t afford a world tour’s price of air tickets, hotels, and meals this year, know that Panasonic has worked up technology to bring the world to you. Its system is titled “DIVE into World Heritage 3D,” and it was demonstrated at Digital Content EXPO 2012. This system put five 3-D cameras to work to shoot, and the display was via five HD plasma panels. “Imaging technology is progressing every day,” Masaru Kojima, manager of Panasonic’s Content Planning Center, told his interviewer. “Today we’re using full high-definition, but in the future pixel counts are likely to grow, as well as the size of the displays themselves.” Panasonic wants to be the “leading edge,” he said, as those kinds of devices become available. The camera is designed for professional videographers who would be attracted to a more affordable and easier-to-use tool than they had in the past. The camera is promoted as an easier way to work than coping with larger-scale setups for capturing content on a professional level. The AG-3DA1 is equipped with dual lenses and two full 1920 x 1080 2.07 megapixel 3-MOS imagers.The camera can automatically recalibrate without the need for external equipment. There is immediate 3-D image capture. The camcorder incorporates stereoscopic adjustment controls; functions for automatically correcting horizontal and vertical displacement are provided, whereas conventional 3-D camera systems required these adjustments to be made by a PC or external video processor, said Panasonic. At less than six pounds, the AG-3DA1 is lighter weight and smaller in contrast to heavy 3-D rigs. Panasonic said the AG-3DA1 is able to perform in extreme environments and stands up better to temperature extremes, shock, and vibration. The company also noted that the camera uses standard, re-recordable SDHC/SD memory cards. © 2013 Phys.org This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Citation: Panasonic steps up 3D camera tech for virtual world tours (2013, January 14) retrieved 18 August 2019 from https://phys.org/news/2013-01-panasonic-3d-camera-tech-virtual.html Panasonic’s “DIVE into World Heritage 3D” is in a strategic partnership agreement with the UNESCO World Heritage Centre to promote the conservation of UNESCO World Heritage sites and to educate children about the world. This system, showing world heritage sites, has been set up in Paris, at UNESCO’s World Heritage Center, at Panasonic centers in Tokyo and Osaka, and at exhibitions to be staged around the world. Panasonic’s technology imaging edge that marks this system is its AG-3DA1 twin-lens 3D camera, an integrated HD 3-D solid-state camcorder which Panasonic described as a “step closer to natural human vision.” last_img read more

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Why do mitochondria retain their own genome

first_imgIt sounds like science fiction to suggest that every cell in the human body is occupied by a tiny genome-equipped organelle, with which we exist in symbiosis. But in actuality, eukaryotic life is dependent on mitochondria, which provide energy to the cell in the form of adenosine triphosphate (ATP). Over millennia, the genomes of mitochondria evolved under selection for minimal gene content, but researchers have been unable to determine why some but not all mitochondrial genes have been transferred to the nuclear genome. An international collaborative of researchers formed an interesting hypothesis regarding this phenomenon: The mitochondrial genome encodes hydrophobic membrane proteins which, if encoded in the nucleus, would be filtered by the signal recognition particle (SRP) and misdirected into the endoplasmic reticulum. The researchers conducted a study exploring their hypothesis and have published their results in the Proceedings of the National Academy of Sciences. In order to predict if a protein would be targeted by SRP, the researchers calculated the free insertion energy of transmembrane proteins, which, if scored zero or less, were considered to be hydrophobic. Higher scores were rated marginally hydrophobic. If a transmembrane protein domain (TMD) scored hydrophobic and the length of its tail was longer than 120 amino acids, the researchers predicted it would be arrested by SRP and directed into the endoplasmic reticulum.They expressed such proteins in cellular cytoplasm and were able to determine that they were, in fact, arrested by the SRP and directed to the endoplasmic reticulum. Further, the researchers observed that the mistargeting of these hydrophobic proteins into the soluble medium of the endoplasmic reticulum resulted in the formation of aberrant honeycomb structures similar to those observed during viral infections. “We conclude that genes for hydrophobic membrane proteins of more than 120 amino acids are likely retained in distinct organelle genomes to ensure a correct localization of these proteins and avoid transport to the endoplasmic reticulum,” the authors write.Thus, the researchers conclude, the selection against mistargeting hydrophobic proteins into the endoplasmic reticulum posed at least one major selective constraint on the retention of the mitochondrial genome. They bolster this finding by comparing it to similar membrane dynamics in the chloroplasts of plants.Previous studies have suggested that one-third of mitochondrial proteins have evolved in response to the specific environmental constraints of different species. Most of these proteins are involved with transport, regulatory, and membrane functions. The results of the current study are consistent with these findings. A persistent mystery has been the evidence that in rare cases, transfers of otherwise universal mitochondrial genes into the nuclear genome have occurred. The results of the current study present an explanation: These particular proteins demonstrate reduced hydrophobicity in those species in which the transfer took place.Clinical applications include the development of methods to cure human mitochondrial genetic diseases, such as Leber’s hereditary optic neuropathy. “These results resolve the long-standing question about why aerobic mitochondria and photosynthetic chloroplasts need a distinct compartmental genome, by and large, although other factors may be involved,” the authors write. Journal information: Proceedings of the National Academy of Sciences © 2015 Phys.org This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. More information: “Mitochondrial genomes are retained by selective constraints on protein targeting.” PNAS 2015 ; published ahead of print July 20, 2015, DOI: 10.1073/pnas.1421372112center_img Mitochondria. Credit: Wikipedia commons Structural data reveals new mechanism behind protein transport Citation: Why do mitochondria retain their own genome? (2015, July 24) retrieved 18 August 2019 from https://phys.org/news/2015-07-mitochondria-retain-genome.html Explore furtherlast_img read more

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Osteoblastic lysosome plays a central role in mineralization

first_img Nanoscale observation of live osteoblasts in culture media, using the SE-ADM system. (A) Representative high-resolution SE-ADM images of osteoblasts cultured with or without osteogenic media for 2 days. Black particles were evident only when cultured in osteogenic media (right, square in the bottom). (B) Representative high-resolution SE-ADM images of osteoblasts cultured with or without osteogenic media for 7 days. There are many black particles when cultured in osteogenic media (right). (C) Representative high-resolution SE-ADM images of the SiN film after cell removal. In normal media, no particles are observed (left). The image of the film after removal of cells cultured in osteogenic media shows many clear black particles dispersed in the whole area (right). (D) Comparison of particle images during 4 to 10 days of culture in osteogenic media. The particle sizes gradually increased. (E) Distribution of particle size measured during 4 to 10 days of culture in osteogenic media. Approximately 900 to 1100 particles per time point were measured and plotted as a histogram. (F) Representative high-resolution SE-ADM images of osteoblasts cultured with osteogenic media for 7 hours. (G) MVBs have clear gray envelopes. (H) Cut images of various MVB sizes, including particles. (I) Comparison of MVBs with or without a gray envelope. (J) Schematic view of intracellular formation and transport of MVB in mineralizing osteoblasts. Scale bars, 1 μm in (A) to (C) and (F); 500 nm in (G); 200 nm in (D, bottom), (H), and (I). Credit: Science Advances, doi: 10.1126/sciadv.aax0672 Mineralization is mediated by osteoblasts, which secrete mineral precursors through matrix vesicles (MVs) as a fundamental process in vertebrates. The vesicles are calcium and phosphate rich, containing organic materials such as acidic proteins. In a new study now published in Science Advances, Tomoaki Iwayama and colleagues at the departments of periodontology, biomedical research, oral science, biomaterials and oral anatomy development used scanning electron-assisted dielectric microscopy (SE-ADM) and super-resolution microscopy (SRM) to assess live osteoblasts during conditions of mineralization at nano-level resolution. They found the calcium-containing vesicles to be multi-vesicular bodies containing mineralizing nanovesicles or matrix vesicles (MVs). According to the observations, the MVs could be transported together with lysosomes and secreted by exocytosis. Iwayama et al. presented proof that the lysosomes could transport amorphous calcium phosphate in mineralizing osteoblast cells. Super-resolution live imaging of calcium containing vesicle transports via lysosomes. (A) Snapshot of time-lapse SRM images of calcein-labeled osteoblasts. Cells were cultured with calcein and stained with Lysotracker and MitoTracker. White arrows indicate colocalization of lysosomes and calcein-positive vesicles. (B) Close-up of time-lapse SRM images of calcein-labeled osteoblasts. Red arrowheads indicate lysosome, and green arrowheads indicate calcein. Once lysosomes fused to calcein-positive vesicles adjacent to mitochondria, they started to move toward extracellular space. (C) Representative SRM image of LAMP1-mCherry–expressing cells. Cells were transfected with LAMP1-mCherry plasmid, cultured with calcein, and stained with MitoTracker. Calcein-positive vesicles matched to LAMP1-mCherry–positive lysosomes. (D) Schematic view of lysosomal involvement in transportation of calcium in mineralizing osteoblasts. Scale bars, 2 μm in (A), 1 μm in (B), and 10 μm in (C). Credit: Science Advances, doi: 10.1126/sciadv.aax0672 Scanning electron-assisted dielectric microscopy (SE-ADM) observation of osteoblasts. (A) High-resolution SE-ADM set up for osteoblast observation. Liquid-sample holder including osteoblasts is mounted on the pre-amplifier-attached stage, which is introduced into the specimen SEM chamber. The scanning electron beam is applied to the W-coated SiN film at a low acceleration voltage. Measurement terminal under the holder detects electrical signals through liquid specimens. Clear intracellular structures are visible (right image). Credit: Science Advances, doi: 10.1126/sciadv.aax0672 Characterization of mineral containing vesicles. (A and B) High-resolution particle images before (A) and after (B) removal of cells cultured in osteogenic media for 7 days. Pseudocolor maps of enlarged particle images indicated by red arrows are shown on the right side of (B). Particles show very smooth structures without crystals. (C) Scanning electron microscopy (SEM) images and EDX spectrometric analysis of particles on a SiN film. SEM image on the left side exhibits the SiN film after removal of cells cultured in normal media, which shows no particles, and EDX spectrometric data show no peaks of phosphorus and calcium. In contrast, the SEM image and EDX spectrometric data on the right side show particles and sharp peaks of phosphorus and calcium after culture in osteogenic media. (D) Analysis of particle elements using EDX spectrometric maps. Particles contained phosphorus, calcium, carbon, and nitrogen. (E) Raman spectra obtained from osteoblasts cultured with or without osteogenic media for 23 days. Sharp peak of 960 cm−1 was evident only in osteogenic media (right side). a.u., arbitrary units. (F) Comparison of SE-ADM images of Alpl knockout (KO) osteoblasts in normal and osteogenic media. Particles completely disappeared in osteogenic media. (G) EDX spectrum of particles from Alpl KO osteoblasts on a SiN film. Left-side EDX spectrometric data exhibit the SiN film after removal of cells cultured in normal media, which show no peaks of phosphorus and calcium. Moreover, particles in osteogenic media of right-side data show no peaks in phosphorus and calcium. Scale bars, 1 μm in (A), (C, top), (D), and (F); 200 nm in (B); 100 nm in (B, right). Credit: Science Advances, doi: 10.1126/sciadv.aax0672 Lysosomal inhibitors block mineralization. (A and C) Confocal live imaging of 50 nM BafA-or 10 μM Vac-1–treated osteoblasts. Cells were cultured in osteogenic media containing BafA or Vac-1 and stained with Hoechst 33342 and LysoTracker Insets show higher magnification and boxed area of each channel. (B and D) SD-ADM images of BafA- or Vac-1–treated osteoblasts. Cells were cultured in osteogenic media containing BafA or Vac-1. (E) Alizain Red S staining performed without fixation. Cells were cultured in osteogenic media containing BafA or Vac-1 and stained with Alizain Red S. Representative confocal images. Scale bars, 50 μm in (A), (C), and (E); 2 μm (B) and (D). Credit: Science Advances, doi: 10.1126/sciadv.aax0672 To overcome these limitations in the present work, Iwayama et al. used a new microscopic system known as scanning electron-assisted dielectric microscopy (SE-ADM). The method had previously achieved nanoscale resolution and high-contrast imaging for mammalian cells in aqueous media without staining. The scientists used the same technique (high resolution SE-ADM) to explore the possibility of viewing MVs in intact osteoblasts to understand biogenesis of MV trafficking. For the osteoblast cell line they used murine (mouse) osteoblastic cell line KUSA-A1, with high osteogenic capacity in vitro and in vivo. After cell culture under adequate conditions, Iwayama et al. observed the cells with SE-ADM to identify normal intracellular structures. The scientists observed MVs to align with collagen fibrils after 4 to 10 days of cell growth in osteogenic media and the secreted particle size increased due to fusion or particle growth, with their sizes consistent with previous reports to suggest they were indeed MVs. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Explore further New pathway for cell communication discovered , Bone Citation: Osteoblastic lysosome plays a central role in mineralization (2019, July 11) retrieved 18 August 2019 from https://phys.org/news/2019-07-osteoblastic-lysosome-central-role-mineralization.html Journal information: Science Advances After directly observing the production and secretion of MVs using SE-ADM, the scientists further investigated the involvement of lysosomes in intracellular trafficking of MVs to observe live osteoblast mineralization. They cultured the cells in calcium-containing osteogenic media and stained them with LysoTracker to detect the intracellular components of interest. Iwayama et al. located the calcein-fulfilled vesicles matched with lysosomes to suggest the biogenesis of MVs within lysosomes after their fusion with calcein+ vesicles. The scientists followed the experiments with loss-of-function and functional inhibition studies to further deconstruct the pathways and examine intracellular mechanisms of action during live cell mineralization in vitro. Upon further examination with SE-ADM, they noted the involvement of the lysosomal pathway to transport and secrete intraluminal MVs in a similar process to exosomes. Interestingly, both exosomes and MVs are categorized as extracellular vesicles with similar sizes; they are both secreted by osteoblasts and have shared functions during cell-cell communication. Scientists had previously reported the involvement of mitochondria during mineralization due to the presence of electron-dense calcium and phosphorous-rich granules in osteoblast mitochondria. This was observed with a modified cryotechnique. Furthermore, reports also suggest the direct contact of lysosomes and mitochondria with functional significance. When Iwayama et al. stained cells with LysoTracker together with MitoTracker and observed the intracellular components under N-SIM structured illumination super-resolution microscopy (SRM). They observed the presence of most calcein-fulfilled vesicles next to mitochondria and matched with lysosomes. During SRM-time lapse imaging, the scientists further obtained views of intracellular transport of LysoTracker containing vesicles fused to static calcein vacuoles adjacent to mitochondria to validate their hypothesis. In this way, together with observations of other SRM systems and additional cell lines, Tomoaki Iwayama and colleagues proposed a mineralization mechanism. Wherein lysosomes played a central role in intracellular MV biogenesis and trafficking within osteoblasts. It was reasonable to involve lysosomes for osteoblasts to transport amorphous calcium phosphate without crystallization during its transport in the cytosol. The scientists aim to conduct further experiments to understand the regulatory molecules for MVs and investigate if MVs and exosomes have similar constitutions and mechanism underlying their generation, secretion and function. The SE-ADM strategy used in the present work can be installed into existing scanning electron microscopy apparatus at a low cost. The work developed in the study will offer non-invasive, high-resolution imaging at the nanoscale applicable to all scientific fields. In the next step, Iwayama et al. examined if these particles were MVs containing calcium and/or phosphate. For this, they cultured the cells in osteogenic media for 7 days and observed them using SE-ADM to record very smooth structures without crystal facets. This suggested that the MVs did not crystallize but remained amorphous as also recorded in a previous study. When the scientists examined the MVs on a SiN (silicon mononitride) film, they observed sharp peaks corresponding to phosphorous, calcium, carbon and oxygen elements. They confirmed the findings using Raman spectroscopy to show the presence of calcium phosphate within MVs. The scientists also investigated the effects of hypophosphatasia a medical condition encoded by the Alpl (alkaline phosphatase) gene, wherein osteoblasts do not undergo mineralization in vitro. For this, they edited the genome of osteoblast cells using the CRISPR-Cas9 genome editing technology to generate Alpl knockout osteoblast clones. When Iwayama et al. examined the knockout clones using high-resolution SE-ADM, they did not observe MVs, which was further confirmed using spectrometric analysis due to the absence of phosphorous and calcium peaks. © 2019 Science X Network , Science During the physiological process of bone mineralization, the deposition of calcium phosphate crystals occurs in the extracellular matrix as a fundamental process in all vertebrates. In 1967, biologists Clarke Anderson and Ermanno Bonucci, individually visualized mineral-related particles in the extracellular space using electron microscopy (EM). Scientists later recognized these particles as mineralizing nano-vesicles or matrix vesicles (MVs). During the past 50 years of EM studies on MVs, biologists have grappled to understand the mechanism of MV formation and secretion, which remains largely unknown. Clarifying the mineralizing process of live cells with EM is challenging since sample preparation for EM requires steps on both chemical fixation and alcoholic dehydration. The steps can induce artefacts and even dissolve or remove unstable mineral precursors leaving an organic scaffold known as a “crystal ghost”. While scientists had successfully used the process of EM using fixed and dehydrated tissue to view the structure of mineralized collagen fibrils in bone, to study mineral precursors, they must employ cryo-EM processes to avoid dehydration and facilitate costly, extremely fast cooling with small specimens. More information: Tomoaki Iwayama et al. Osteoblastic lysosome plays a central role in mineralization, Science Advances (2019). DOI: 10.1126/sciadv.aax0672 N. Reznikov et al. A materials science vision of extracellular matrix mineralization, Nature Reviews Materials (2016). DOI: 10.1038/natrevmats.2016.41 Natalie Reznikov et al. Fractal-like hierarchical organization of bone begins at the nanoscale, Science (2018). DOI: 10.1126/science.aao2189 Irving M. Shapiro et al. Matrix vesicles: Are they anchored exosomes?, Bone (2015). DOI: 10.1016/j.bone.2015.05.013last_img read more

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The youth gala

first_imgThe youth festival 2013, that is going on in the Capital, is empowering the country’s young achievers. It is also providing them with a national platform to showcase their talent. The festival is bringing together a truly Indian extravaganza of dance, drama and music for youngsters.The festival stages together an array of dance forms that depicts the flavour of India. Young and talented artists and groups, from all over the country, are participating in the event. Be it contemporary, classical or folklore – there’s a lot of action to watch out for in every segment of the festival. Youth bands selected from different states and cities are set to take the festival on a much higher note. Also Read – ‘Playing Jojo was emotionally exhausting’‘We are extremely overwhelmed to see the kind of acknowledgement this festival is receiving from people of all ages in the city. The crowd, the hoots and the appreciation from the audience on each day, says it all’, said Sindhu Mishra, Deputy Secretary of Sahitya Kala Parishad.She moves on to explaining the concept of the festival further. There are many independent groups/institutes in our country who are continuously helping the youngsters with adequate training in different art forms. Then, there are youth bands who have their own unique take on music and a huge fan following. ‘Our country has a bunch of talent waiting to get explored. At the same time, these young dancers, musicians, cultural groups and trainers, need support and the right kind of exposure. The youth festival acts like their backbone and give them the platform to showcase their talents and the culture,’ she added. Also Read – Leslie doing new comedy special with NetflixGiving the ongoing festival a much-needed edge, an exhibition showcasing the best artworks by young artists from various art colleges of Delhi is also up for display and exploration.As part of their many endeavours to keep the roots of our country intact, the Delhi government’s Department of Art, Culture and Language celebrates this festival annually to make sure that our young achievers are recognised and encouraged and take their talents seriously. It also, in turn, brings a reason for celebration. Groups like Sadhya, Bhoomika, ASPA, Abhinay dance company, Tapasya among others are taking on the contemporary juncture in full swing. Music bands including Secret Weapon, Indian Saber, Three the People, Daksha, to name a few, will musically empower the festival in coming days.In the classical segment, dance forms like Kathak, Oddissi, Manipuri, Mohiniattam, Chhau, Kuchipuri, Bharatnatyam and Kathakali will be performed by young birds from all across the country, reflecting the true culture of our country.Also Murad’s Sarangi, Akram Khan’s Tabla, Ajay Kumar’s ritual drum, Anupriya’s Parinday band playing the violin and Pt Bhajan Sapoori’s Santoor will ensure classical music gets its due at the Youth Festival, on all days.When: Till 1 DecemberWhere: Central Park, Connaught Placelast_img read more

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The spirit of joy

first_imgChristmas and New Year are magical times and to usher in the festive season. Shangri-La’s – Eros Hotel, New Delhi hosted its Annual Christmas Tree Lighting Ceremony in the Hotel Lobby on Friday, December 12. The spirit of Christmas was shared by in-house guests and other luminaries from various walks of life. Guests were offered Santa hats as they stepped into the lobby. The imposing Christmas tree was unique. It has been laboriously and artistically made from dried rubber plant leaves, beautifully painted in hues of gold by our in -house florist. The team painstakingly worked for three months to create this gigantic environmentally friendly Christmas tree keeping in line with the Hotel’s green initiative. Also Read – ‘Playing Jojo was emotionally exhausting’Guests were treated to delectable Christmas delights, such as chocolate Santa, plum cake, candies, gingerbread cookies and mulled wine as they immersed themselves in the festive spirit. After the lighting of the Christmas tree by Farhat Jamal and children, Santa came through his chimney and went straight into the Lobby to give out goodie bags to all the excited young ones. The sounds of Jingle Bell Rock’, ‘Joy to the World’ and ‘Santa Claus is coming to town’ by young carollers from St. Ann’s choir reverberated through the Lobby as everyone sang along to the popular carols. After the ceremony, guests were invited for a pre Christmas celebration over Christmas delicacies, canapes and wine as they enjoyed the popular tunes being belted out by the live band.last_img read more

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Class XII girl streams her own suicide on social media

first_imgKolkata: In a sensational incident, a class XII girl from South 24-Parganas’s Sonarpur went live on a social networking site and showed the way she committed suicide by hanging herself from the ceiling fan at her house.The victim, Mousumi Mistri was a student of Sonarpur Kamrabad School. The incident took place in Baidyapara area of Sonarpur. The incident triggered tension in the area. Police on Monday morning recovered the body from the house and sent the body for postmortem. Also Read – Heavy rain hits traffic, flightsAccording to police, the victim had an affair with a local youth for quite some time. Police came to know in the course of the investigation that the victim on Sunday afternoon received a phone call from one of her friends and left the house. She told her mother that she would return home by 5 pm. Though, she returned home at around 6 pm. After returning, she did not talk much. Her mother, Shampa Mistri who works as an Ayah left the house a little after 6 pm. Later, she went to attend a cultural programme that going on in the locality and returned home at around 9.30 pm. After having her dinner, the girl went to her sleep in her room and closed the door. The victim’s father and younger brother live somewhere else and the victim used to live with her mother. Also Read – Speeding Jaguar crashes into Merc, 2 B’deshi bystanders killedAs the girl did not open the door till 8.30 am on Monday morning despite her mother’s repeated knocks on the door, she informed locals, who broke a portion of the window to see the victim hanging from the ceiling fan. The girl generally got up within 8 am. After being informed, police reached the spot and recovered the body. Police said before committing suicide she spoke to her boyfriend through video chat on a social networking app. Police have started a detailed probe into the incident. They are yet to ascertain the exact cause.last_img read more

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Robust defence important for hockey team

first_imgIndia’s men’s hockey chief coach Roelant Oltmans on Tuesday said that a well-organised defence will hold the key for the team’s fortunes in next year’s Rio Olympic Games.Oltmans, who is doubling up as High Performance Director and head coach after the ouster of Paul van Ass, said that he was working on building a solid defence and switching to different styles of play in different situations.“Organisation of defence is very important. If your defence is well organised you have confidence while going for attack. If your defence is not well organised you can be in trouble in counter attacks,” Oltmans said here. Also Read – A league of his own!The Indian men’s team is here for a three-week training stint till September 27 before leaving for New Zealand for a hockey Test series.Asked about other areas which he would want to improve in the Indian team, he said, “We want to be unpredictable and dynamic, to be able to play in different styles according to different situations.”“In France and Spain (where the team toured recently), we tried to implement these things. We have very good players in attack who scored some very good goals like the one by Akashdeep and Ramandeep. We have rooms for improvement in attack. It’s good to have some series in line so that we can see how we can apply these changes.”Asked if the Indian team was progressing in the right direction with less than a year left for the Rio Olympic Games, he said, “In India people always looked for results but we cannot always think about the result. The process is important.last_img read more

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Panorama of artist Senakas works

first_imgWriters express themselves through their writings, musicians through their music but for an artist, his work, whether be it a painting, a portrait or just a drawing, speak to a great length not only about his feelings but of others as well.Grosvenor Gallery will showcase its works for the sixth consecutive year at the 8th edition of the India Art Fair from January 28-31. This year the gallery will be exhibiting new paintings by one of South Asia’s premier artists, Senaka Senanayake.  Also Read – ‘Playing Jojo was emotionally exhausting’The work by renowned artist Senaka Senanayake, titled ‘Ganesh’, will be published in an edition of 100 and will be available for the first time at the India Art Fair. The piece is exclusive to Grosvenor Gallery, which will not be available anywhere else.Senaka achieved early fame as a child prodigy, whose work was first exhibited in Colombo in the late 1950s. He then held his first international one man show in New York at the age of 10. He continued to paint and as a teenager held numerous exhibitions in Sri Lanka as well as Europe, the USA and Asia. His recent work is inspired by the plight of the Sri Lankan rainforests, many of which have been a subject to intense deforestation to make way for tea-plantations.  Also Read – Leslie doing new comedy special with NetflixOne of Senaka’s objectives is to establish a connection with everyone that encounters his work. “Many times, people can’t relate to a piece of art  as the artworks don’t respond but I want my paintings to talk. Everyone, from a street sweeper to a university professor, should be able to relate to my art”, said Senaka.It takes almost 2-3 weeks for his canvas to get completed. Layer upon layer of paint is added, creating an incredible depth to the colours and imparting a rich feel to the works, which appear to have an almost luminescent quality to them. When asked about his work, the artist commented: “My main focus is on the endangered flora and fauna in our rainforests. In 2005, I visited a rainforest in Sri Lanka, which had become my muse for many of my shows. I could have shown the negative aspects of destruction, such as people and animals dying, but I try to create happy and positive paintings.”When: January 28 – 31Where: NSIC Grounds, Okhla Industrial Area, New DelhiTimings: 11 am to 7 pmlast_img read more

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