“Ensuring a functional UN that is capable of effectively addressing diverse global issues is of the utmost importance,” Prime Minister Naoto Kan told the General Assembly’s annual high-level debate, which entered its second day today.Member States, he said, must take proactive steps to promote the world body’s reform, while the UN, for its part, must ensure its own transparency and accountability.Mr. Kan pointed to the creation of UN Women – or the UN Entity for Gender Equality and the Empowerment of Women – as a “test case for the promotion of effective and efficient activities” of the world body.Created by the Assembly on 2 July, UN Women, headed by former Chilean president Michelle Bachelet, will oversee all of the world body’s programmes aimed at promoting women’s rights and their full participation in global affairs.UN Women is the merger of the UN Development Fund for Women (UNIFEM), the Division for the Advancement of Women (DAW), the Office of the Special Adviser on Gender Issues, and the UN International Research and Training Institute for the Advancement of Women (UN-INSTRAW).The Japanese Prime Minister today underscored the key role played by the Security Council in helping the UN resolve global challenges, calling its reform “indispensable.”His country, he said, as the only country that has ever been devastated by atomic bombings and does not possess nuclear weapons, is “well-suited to play a role in the Security Council in the 21st century.”Mr. Kan underscored “Japan’s determined aspiration to take on further responsibilities for international peace and security as a permanent member” of the Council.In his address, he also urged stepped-up will and action in the arena of nuclear disarmament and non-proliferation, pointing to recent strides, including Ban Ki-moon’s visit to the Hiroshima Peace Memorial Ceremony, making him the first Secretary-General to take part in the event.“Japan bears a responsibility to all humankind to hand down to future generations an awareness of the catastrophic nature of nuclear weapons,” the Prime Minister said, adding that the country will coordinate with other countries to promote education on disarmament and non-proliferation.On the Democratic People’s Republic of Korea (DPRK), he said that the country’s nuclear and missile development programmes are a threat to the entire world, calling on it to take measures in line with relevant Council resolutions and the Joint Statement of the Six-Party Talks, involving China, DPRK, Japan, the Republic of Korea, Russia and the United States.Under that September 2005 agreement, the DPRK committed itself to abandon nuclear weapons and rejoin the Nuclear Non-Proliferation Treaty (NPT).Japan continues to endeavour to normalize relations with the DPRK, and towards that end, “it is absolutely indispensable to resolve the abduction issue,” Mr. Kan stressed, referring to the abduction of Japanese citizens in the late 1970s and early 1980s.“If the DPRK takes constructive and sincere steps such as implementing its agreement with Japan, Japan is ready to respond in kind,” he said.During the Japanese leader’s meeting with Mr. Ban today, the two men agreed on the need to continue efforts to revive the Six-Party Talks, as well as the close cooperation of the concerned parties.The Secretary-General expressed his appreciation for Japan’s continued support in areas including climate change, Afghanistan, Haiti and Sri Lanka.They also discussed the Millennium Development Goals (MDGs), biodiversity, UN reform and Japan’s support for UN peacekeeping operations. 24 September 2010Underscoring the centrality of the United Nations in promoting peace and prosperity, Japan’s leader stressed today that the Security Council must be reformed to reflect the international community’s current realities.
TORONTO — Bank of Montreal says it expects to grow its U.S. mergers and acquisitions business through the purchase of a Minneapolis-based advisory firm, which will become part of BMO Capital Markets.The bank says it has a definitive agreement to acquire Green Holcomb Fisher, a boutique M&A advisory firm.BMO says the financial terms aren’t being made public. The deal requires regulatory approvals and is expected to close by the bank’s fiscal fourth quarter ending Oct. 31.Brookfield Asset Management raises $4 billion war chest for latest private-equity spinoffCanada’s banks still looking good as earnings season winds downCIBC, Scotia deepen relationship with Montreal fintech player Thinking CapitalBank of Montreal says Green Holcomb Fisher will complement its existing U.S. mergers and acquisitions practice and double the number of M&A transactions it handles in the United States.Besides its head office in Minneapolis, Green Holcomb Fisher has offices in Seattle and Atlanta.
MINNEAPOLIS — A Delta Air Lines pilot has been charged with operating an aircraft under the influence of alcohol.The criminal complaint against Gabriel Schroeder, of Rosemount, Minnesota, says tests determined the 37-year-old had a blood alcohol level between 0.04% and 0.08% when detectives arrested him on a plane at the Minneapolis airport, just as it started boarding for San Diego July 20. The limit set by the Federal Aviation Administration is 0.04%, which is half the legal limit for driving in Minnesota.Schroder was charged Friday. His first court date is Nov. 27. Court records don’t list an attorney who could comment for him.The complaint says Schroeder told detectives that he’d had one beer and three vodka drinks the night before. He also admitted discarding an unopened vodka bottle investigators found in an airport bathroom after he saw that security screening for crews had been stepped up.The Associated Press
Maryland and South Carolina have really good women’s basketball teams — two of the four best in the country. But Connecticut and Notre Dame, their respective Final Four opponents on Sunday in Tampa, are a cut above. They’re ranked No. 1 and 2 in the country by the AP, the coaches and the tournament selection committee. They’re the favorites to reach Tuesday’s final in our March Madness predictions and in Vegas. They played each other in last year’s final. And, best of all, they have a rich history — one that isn’t as one-sided as UConn’s recent dominance suggests.Notre Dame has dealt UConn seven of its 18 losses since the start of 2007. In other words, 39 percent of the time UConn has lost in the last eight-plus years, it’s been against Notre Dame.If UConn and Notre Dame play each other in the final, it’d be their 21st meeting since the start of 2007 — the latest ESPN Stats & Info data available. They played 12 regular-season games (11 back when both were in the Big East), plus three Big East conference finals and one semifinal. They’ve also met four times in the last eight Final Fours, with two wins apiece. A Tuesday meeting would be the rubber match.Maryland and South Carolina have been good, but they simply haven’t been as dominant. UConn has won 94.6 percent of its games since the start of 2007, by far the best in the sport. Notre Dame ranks fifth, at 84.1 percent. (Stanford, Green Bay and Baylor are second, third and fourth.) Maryland is 11th, at 80.6 percent. And South Carolina is 53rd, at 64.3 percent. But South Carolina’s and Maryland’s relative inconsistency, coupled with UConn’s and Notre Dame’s late, lamented conference rivalry, means they have a much thinner record against the rest of the Final Four.So let’s look more closely at the UConn-Notre Dame rivalry. UConn has won 13 of their last 20 matchups, or 65 percent. That’s as close as UConn gets these days to a balanced rivalry — it’s the lowest winning percentage UConn has against any team it has played more than five times since the start of 2007. Every team but one that has played UConn at least once in that time has a losing record against the Huskies. (The one exception is longtime rival Tennessee, which won their only recent meeting.) More than 90 percent of UConn opponents haven’t beaten the Huskies even once, including four teams that have played them at least 10 times.Also notable, for a team that has regularly all but clinched its games by halftime, UConn has beaten Notre Dame by an average of less than eight points per game in their 20 meetings. That’s the closest average margin for any UConn opponent that has played the Huskies more than five times since 2007.UConn, meanwhile, is responsible for a big chunk of Notre Dame’s losses since the start of 2007: 13 of 49, or 27 percent. UConn is the only team Notre Dame has played in more than six games in that period that has a winning record against the Fighting Irish.Notre Dame’s recent wins against UConn all came in an astonishingly short spell: The Fighting Irish won seven of eight meetings over a stretch that started with Notre Dame’s upset of UConn in the 2011 Final Four. Notre Dame star Jewell Loyd, a junior and the team’s leading scorer, is the only current player who was a major contributor for the Fighting Irish when they last beat UConn.It’s not the most heated or longstanding rivalry. Before the teams played in December — in a game UConn won by 18 points — espnW’s Graham Hays pointed out that it doesn’t have the rich character and tension of UConn-Tennessee. Notre Dame head coach Muffet McGraw, asked before the game about her relationship with Connecticut coach Geno Auriemma, made it sound like the two were friendly acquaintances in the corporate world. “Geno and I are terrific,” McGraw said. “We saw each other this summer. We’ve got no issues, no problems. Just business as usual for both of us.”If it’s business as usual for both teams on Sunday, we’ll see them renew their acquaintance in the final on Tuesday in Tampa, in the latest edition of the closest thing to a rivalry that Auriemma’s dominant UConn team has these days.
IT’S A BUSY day in Oireachtas: Enda Kenny will be taking TDs’ questions at 3.15pm, a Fianna Fáil bill on access to credit will be discussed and there’s the issue of the controversial Freedom of Information Bill, which reaches committee stage this afternoon.However, how much of what the average citizen will be able to watch and hear remains to be seen; the Oireachtas website is currently suffering from a range of “technical issues”.On some browsers, this means its not possible to view the site at all, while on others users are reporting problems visiting certain sections.An Oireachtas spokesperson said the issue was due to a full server, and that staff were currently working through the problem.“It’s something we’re hoping to have fixed as soon as possible,” the spokesperson said.“Certain sections are coming back to life as they work through the problem.”He said the Oireachtas Communications Department had been fielding a “large number” of calls on the issue, mostly from people asking about today’s schedule for the Dáil, Seanad and committees.Read: Freedom, credit and everything else happening in Leinster House todayRead: Department’s FOI amendments ‘run entirely contrary to spirit’ of bill
If it wasn’t clear before this week, it should now be apparent that the battle between Google and Facebook is about the future of the web as we know it. Both of these companies are vying for the attention span of users across the globe. Facebook and Google both want one thing above all else, and that is for you to be using their services all day, every day. The more you are tied into their tools, the more data they can collect, and the more ads they can deliver. At the end of the day, that means being able to provide users with the best social experience. While Google+ is certainly making headway, this is still and are in which Facebook is king. However, in an attempt to shift the scales once more, Google has released a massive user interface update to Google+, which is rolling out to users worldwide right now.Google’s push into the social space has been fairly successful so far. By integrating Google+ into all of their existing products, the search giant was able to announce today that there are over 170 million accounts on G+. (There’s no accurate metrics as to how many of those users are active.) Unlike Facebook, Google+ relies on a user’s ability to find other people with common interests and socialize with them. Facebook, on the other hand, relies on the information you provide them to find other users with which you share a past connection, typically through school or work.Typically, huge user interface overhauls are met with mixed emotions. Users who don’t like change versus users who embrace anything new muddy the general opinion of major changes, but like it or not change has come to Google+. And it’s a different tact for Google+, which has been continually evolving from day one, improving the experience with new or modified features nearly every week.Google has taken their social network and stretched it out a bit, moving a few things around to create a more streamlined look and feel. The chat tool has been moved to the far right, allowing the list of active instant messenger users go all the way down this side of the page. This is a huge improvement for anyone who has more that fifteen users on their list, which was a previous limitation of the chat implementation.The information in your stream still occupies the majority of the interface, only now every post has been placed in its own little container. Each post feels much cleaner, right down to the compact view of the comments for each post. A single comment is shown, unless you expand the comment field to see more of them. Above your stream are tabs for quick access to posts that are only in specific circles, allowing you to break up your stream and quickly access the information being displayed inside those circles. Finally, the navigation panel on the left hand side is adjustable based on your preference.If you play a lot of Google+ games, or if you prefer Hangouts and Photos at the top of your navigation bar, it is quick and easy to change it to suit your experience.Personal profiles received a big style update as well. Aside from your avatar photo, there’s not a space for a Timeline-esque top photo. Users who stumble upon your profile will have a separate navigation for your posts, profile, and photos as usual, but will now also have access to things you have +1’d. The profile view now also includes information such as how many people are in that users circles, and how many users have circled them back. At the top of the profile view there is a small email icon, which ties into the already existing email feature to Google+ that hides the users email address but still allows you to contact them. All of the information in the profile view is tucked neatly inside the same box that contains your stream information on you homepage, keeping this navigational box Google has built around your content intact.Finally, there is a dedicated page for discovering Hangouts that are already in progress. The Hangouts tab in the navigation panel will let you see public Hangouts that are currently active, as well as users who are in private hangouts but have opened the hangout to a circle that you are in. This is by far the loudest complaint heard by users who are interested in trying Hangouts, but aren’t necessarily comfortable starting one of their own. Being able to see active Hangouts means that the users can hop in as they please and enjoy the social experience, without having to catch the invitation to the Hangout in their stream. More people using Hangouts means more people using Google+, so everyone wins.Google has performed a serious operation, by changing nearly every facet of the user interface. While it is obvious that this update has been in the works for some time, the delivery of this update only a day after Facebook announced the acquisition of Instagram can’t be a coincidence. Unfortunately, user interface improvements are really great for keeping your existing users, but Google needs to now focus on gaining new users. I can’t remember ever seeing a commercial for Facebook on television, but I typically see one for Google+ every couple of days. As social networks go, Google+ is my favorite for extended conversations with people, and the Hangouts system has proven time and again to be an invaluable resource.
Good news, Ubuntu Edge supporters! The Indiegogo campaign finally chalked up its first $80,000 Enterprise 100 bundle. The bad news: there’s little hope that the remaining $20 million+ can be raised in the final two weeks fundraiser.That the seal is finally broken is undoubtedly good news — and it’s even better when you consider that it was international news outlet Bloomberg LP that made the pledge. Having a high profile partner on board is always a good thing, but is it enough to spark a full-blown rally?Even if Canonical manages to fill the remaining 49 Enterprise slots, it’s still got an additional $16 million to make up. It also has to be raised in less time than the first $8.5 million was raised. It’s a Herculean task, to be sure.Funding campaigns like the one for the Edge typically start out hot. Enthusiastic supporters tend to get on board early. It took just 12 hours for the Edge to rake in more than $3 million. One the flip side, it’s now been more than two weeks (or around 336 hours) … and the project has yet to break the $10 million barrier. There’s still time left, of course, and it’s possible that other corporate types will follow Bloomberg’s lead. As I mentioned before, however, that won’t be enough.Maybe a price cut will provide a boost. Canonical has chopped a couple hundred dollars off the Ubuntu Edge perk. It now sits at $695, just $95 more than the initial round of 5,000 phones were reserved for. Then again, that’s a lot of cash to part with for a phone that you won’t see until mid-2014 — and won’t ever see if the funding goal isn’t met.Both Canonical and founder Mark Shuttleworth have said they won’t swoop in at the final hour to save the campaign, either. The corporate stance is “If we don’t reach our target there won’t be an Ubuntu Edge.”At this point, that’s what’s going to happen. Open Analytics shared its projections with The Guardian, and they peg the final tally at somewhere between $18 and $22 million — still well short of the goal. Even with a massive spike in donations come crunch time, the Ubuntu Edge looks like it has a snowball’s chance of becoming reality.
Share Facebook Twitter Linkedin Pinterest Reddit Flipboard Hyperloop, the rapid transit system teased by billionaire investor Elon Musk is going to be unveiled today at 4:30pm. The high speed transportation system has been the topic of speculation for weeks, after Musk tweeted about its pending announcement, talked about it during a Tesla earnings call, and highlighted one engineer’s particularly accurate guess about its design.Musk started off the rampant speculation by saying that Hyperloop would be a “cross between a Concorde and a railgun and an air hockey table.” This led to people creating diagrams and drawing comparisons to both the ET3 transportation project and the Rand Corporation’s 1972 plan for the Very High Speed Transit System (VHSTS) across the United States.A common theme among these projects is that none have been brought to fruition, and though Musk has publically stated that he won’t be the person that builds Hyperloop, today he will reveal the idea and, presumably, make it available to an organization that will (after proper vetting by internet pundits and armchair engineers that is). While the plan seems inherently far-fetched, it’s coming from a man who founded a private space company so, to this point, calls of this being well-publicized vaporware have been minimal.The big reveal is at 430pm, likely on Musk’s Twitter feed. Stay tuned. It’s past 430pm and Mr. Musk has not updated his feed, but Businessweek seems to have been given the exclusive. It’s being reported that there is a wider conference call at 5pm where more information will be revealed. The BW story noted that Musk published a blog post, but it is not available yet.Update: Here is Musk’s blog post. It lays out everything the Businessweek stories explained and included an extremely details PDF which will answer all your questions about the project.Musk released a PDF packed with data, diagrams, and artist renderings. First off, Musk noted that Hyperloop, in theory, could transport cars as well as people. A car would “just drive on” the same way a person would enter a transportation pod. This would be a challenge, of course, and not just for obvious reasons. Musk also confirmed that Hyperloop would have to be elevated in order to keep the path from station to station as direct as possible but also to avoid right-of-way issues with property owners. For those concerned with safety, it’s said that the Hyperloop design would incorporate an emergency brake which would be able to stop a pod in a matter of about five miles, keeping it apart from other pods, regardless of their 700+ mph speeds.Using the popular example of San Francisco to Los Angeles, the total cost would be in the realm of $6B to $10B, with the upper figure being projected if the system could transport automobiles and the lower for just people pods. This is something like one tenth the cost of the proposed California high speed rail system, which would theoretically take about the same amount of time to build.What a pod could look like.And finally, what we all wanted to really know, how does it work? Basically, early guesses weren’t too far off: Hyperloop travels in a low-pressure tube (not a vacuum), in order to reduce drag and increase maximum speeds without consuming huge amounts of power. The pod inside is standing on top of skis, made of an alloy known as inconel, through which air is pumped, just like the reverse of that air hockey table Musk mentioned. Forward movement would be provided by the coolest part of all, an electric turbo compressor which sucks in air from the front and pumps it out of the skis while a electromagnetic pulse system pushes the whole apparatus forward.Comparisons will be made to roller coasters — Space Mountain in particular, thanks to an unfortunate quote in the article — but this does still seem like an interesting possibility and something that wouldn’t be impossible to pull off. That’s not to say it’s any more possible than a $60 or $70B high speed rail system, but the use of technology here — particular in keeping the tube system relatively inexpensive — does have potential.If you want more information, here’s the full 57-page PDF. Elon MuskEt3hyperloopSpaceXtravel
Short URL Tuesday 22 Nov 2016, 9:14 PM A FARMER WHO kept 4 kilograms of cyanide in his shed for 45 years was ‘delighted’ to hand over the stash of killer chemicals.The man had initially purchased the poison to kill rabbits on his farm and had forgotten about it over time.But after discovering it, the man brought it down to a local hazardous waste collection drive in Roscommon where it was disposed of.Experts said it had the potential to kill 65,000 people.Environmental officer with Roscommon council Suzanne Dempsey told Shannonside radio: “We were delighted it was taken off the farm and so was he. He had it there for 45 years in his shed, would you believe it?“He had originally bought it for killing rabbits on his farm but it’s a huge quantity. They are very toxic chemicals. Enough cyanide ‘to wipe out Roscommon’ lay in farmer’s shed for 45 years The farmer brought the killer chemicals down to a hazardous waste collection drive over the weekend. By Garreth MacNamee Image: Wikimedia http://jrnl.ie/3096718 Share1155 Tweet Email3 The Environmental Protection Agency (EPA) are carrying out nationwide events where farmers can get rid of potentially hazardous waste for free.You can find out more information here.Read: Government approves promotions for 11 senior gardaí following controversy >Read: Waterford man knocked down and killed in Antrim collision > Nov 22nd 2016, 9:14 PM 48 Comments The toxic expert on the day said the amount was enough to wipe out most of the county.Environment Minister Denis Naughten had urged farmers to bring down any potentially dangerous chemicals which would have been disposed of correctly.However, he wasn’t expecting the 4kg of cyanide to turn up. Image: Wikimedia Don’t forget hazardous waste collection in Roscommon today- Even one deposit of 4kg of cyanide @TeagascEnviron @EPAIreland @roscommoncoco pic.twitter.com/2XbIeqOhUE— Denis Naughten (@DenisNaughten) November 19, 2016 Source: Denis Naughten/Twitter 43,220 Views Tweet thisShare on FacebookEmail this article
Julen Lopetegui is not a current option for the managerial vacancy at the Mexican national teamThe 52-year old coach is out of work following Monday’s dismissal from his post at Real Madrid after a poor start to the season.Reports in the Spanish press indicated that Lopetegui was being lined up for moves to Russian side Spartak Moscow and Mexico.But ESPN announced that the latter is definitely no option for Lopetegui at this stage after consulting the Mexican football federation (FMF).Furthermore, no contact has been made with Lopetegui whatsoever.Quiz: How much do you know about Hirving Lozano? Tomás Pavel Ibarra Meda – September 6, 2019 Time for you to tell us everything you can answer about Hirving Lozano. We will ask you 10 questions about the Mexican forward. Have…El Tri have been managerless following Juan Carlos Osorio’s departure at the end of the World Cup.Ricardo “Tuca” Ferretti has since been in charge of the national side on an interim basis, until a permanent successor is found.Outgoing Atlanta United manager Gerardo “El Tata” Martino is the favourite to succeed Osorio in the dugout.Despite his ill-fated tenure at Real though, Lopetegui had a successful stint at international level with Spain.He was undefeated in all of his 20 games in charge, which 14 of them were won, before June’s shocking dismissal just days before the World Cup following his appointment as Real manager.
Posted: May 22, 2018 Categories: Local San Diego News FacebookTwitter May 22, 2018 00:00 00:00 spaceplay / pause qunload | stop ffullscreenshift + ←→slower / faster ↑↓volume mmute ←→seek . seek to previous 12… 6 seek to 10%, 20% … 60% XColor SettingsAaAaAaAaTextBackgroundOpacity SettingsTextOpaqueSemi-TransparentBackgroundSemi-TransparentOpaqueTransparentFont SettingsSize||TypeSerif MonospaceSerifSans Serif MonospaceSans SerifCasualCursiveSmallCapsResetSave SettingsPoway Mayor Steve Vaus spoke to Lauren Phinney and Carlos Amezcua about the Poway Hotline, a 24/7 hotline that people can call to report anonymous tips or potential threats to local schools.Any messages left with the hotline are sent to various police and sheriff’s stations for follow up and investigation.Hotline Number: 844-787-3847 Lauren Phinney, Carlos Amezcua Poway Hotline created to help keep students safe Lauren Phinney, Carlos Amezcua,
Two subsidiaries of entertainment organisation The Walt Disney Company are to provide a total of $3.8 million (£3.1 million) in back pay to 16,339 US employees following minimum wage and overtime violations.The US Department of Labor has reached an agreement with the Disney Vacation Club Management Corporation and the Walt Disney Parks and Resorts US to back pay affected employees to ensure compliance with the Fair Labor Standards Act (FLSA).The Wage and Hour Division at the US Department of Labor found that Disney resorts deducted a uniform or costume expense from staff, causing some employees’ hourly rates to fall below the federal minimum wage.In addition, the resorts did not compensate employees who performed duties during a pre-shift period before the designated start of their shifts, or during a similar post-shift period. The resorts also failed to maintain required time and payroll records.Daniel White, district director at the Wage and Hour Division in Jacksonville, said: “These violations are not uncommon and are found in other industries as well. Employers cannot make deductions that take [employees] below the minimum wage and must accurately track and pay for all the hours their employees work, including any time they work before or after their scheduled shifts.“We hope the resolution of this case alerts other employers who may be paying employees in a similar manner, so that they too can correct their practices and operate in compliance with the law.“The Disney resorts were very cooperative throughout the investigative process and worked with the division to ensure employees received the pay they earned.”
APPresident Donald Trump speaks at Mar-a-Lago in Palm Beach, Fla., Thursday, April 6, 2017, after the U.S. fired a barrage of cruise missiles into Syria Thursday night in retaliation for this week’s gruesome chemical weapons attack against civilians. (AP Photo/Alex Brandon)1. GOP REVIVES HEALTH CARE BILLRepublicans are planning a House vote on their prized health care bill, which would let Trump claim a victory six weeks after GOP leaders nearly left the measure for dead.2. PRINCE PHILIP WILL STOP CARRYING OUT ENGAGEMENTSThe 95-year-old husband of Queen Elizabeth II will continue heading numerous charitable organizations but will not play an active role in public events, Buckingham Palace says.3. WHICH IRS RULE TRUMP IS TARGETINGTrump plans to sign an executive order further weakening a rarely enforced agency edict that says churches that endorse political candidates risk losing their tax-exempt status.4. WHO HAS ANTAGONIZED PYONGYANGThe state-run Korean Central News Agency says that “a string of absurd and reckless remarks are now heard from China every day only to render the present bad situation tenser.”5. HOW PUERTO RICO IS ENTERING UNCHARTED TERRITORYUncertainty is spreading across Puerto Rico and the U.S. municipal bond market as the territory takes an unprecedented step into federal court to restructure a portion of its $73 billion debt.6. WHY FRANCE WILL SOON HAVE A LEADER LIKE NO OTHEREither Marine Le Pen, a populist who could dismantle Europe’s post-war unity, or Emmanuel Macron, a political novice, will be president.7. JAILED VENEZUELA ACTIVIST DISPELS RUMORS OF HEALTH EMERGENCYReports that jailed opposition leader Leopoldo Lopez was rushed to a military hospital in a medical emergency sets off a frenzied rush information on the activist, but proved to be wrong.8. WHAT ‘GRAY DEATH’ ISIt’s a new and dangerous opioid combo that underscores the ever-changing nature of the U.S. addictions epidemic.9. WHERE A LAGOON IS DYINGFlorida’s Indian River Lagoon, America’s most biologically diverse waterway, is choked with algae, dead fish, manatees, and bird, because of farm runoff and a huge influx of people.10. LATE-NIGHT HOST DEFENDS TRUMP REMARKSStephen Colbert says he has no regrets about a crude sexual reference regarding the U.S. and Russian presidents that prompted calls to fire him and boycott “Late Show” advertisers. Share
Listen Malene ThyssenOn this episode of Party Politics: Texas Edition, co-hosts Jay Aiyer and Brandon Rottinghaus break down these tumultuous topics in Texas political news:A federal court rules two Texas congressional districts unconstitutionalRepublican caucus talks changes in how to elect speaker of the HouseMillions of people consumed potentially unsafe water in Texas, California, and Oklahoma over the last decadeTexas Aggies cancel planned white nationalist rally on campusThen the profs settle up last week’s wager about how many of Gov. Greg Abbott’s priorities survived the special session because apparently, lawmakers adjourned sine die…for now. By the way, don’t forget to check out our national episodes of Party Politics, too.Party Politics is produced by Dacia Clay, Edel Howlin and Laura Lucas. Our audio engineer is Todd Hulslander. 00:00 /18:39 This article is part of the Party Politics podcast Share X To embed this piece of audio in your site, please use this code:
It sounds like science fiction to suggest that every cell in the human body is occupied by a tiny genome-equipped organelle, with which we exist in symbiosis. But in actuality, eukaryotic life is dependent on mitochondria, which provide energy to the cell in the form of adenosine triphosphate (ATP). Over millennia, the genomes of mitochondria evolved under selection for minimal gene content, but researchers have been unable to determine why some but not all mitochondrial genes have been transferred to the nuclear genome. An international collaborative of researchers formed an interesting hypothesis regarding this phenomenon: The mitochondrial genome encodes hydrophobic membrane proteins which, if encoded in the nucleus, would be filtered by the signal recognition particle (SRP) and misdirected into the endoplasmic reticulum. The researchers conducted a study exploring their hypothesis and have published their results in the Proceedings of the National Academy of Sciences. In order to predict if a protein would be targeted by SRP, the researchers calculated the free insertion energy of transmembrane proteins, which, if scored zero or less, were considered to be hydrophobic. Higher scores were rated marginally hydrophobic. If a transmembrane protein domain (TMD) scored hydrophobic and the length of its tail was longer than 120 amino acids, the researchers predicted it would be arrested by SRP and directed into the endoplasmic reticulum.They expressed such proteins in cellular cytoplasm and were able to determine that they were, in fact, arrested by the SRP and directed to the endoplasmic reticulum. Further, the researchers observed that the mistargeting of these hydrophobic proteins into the soluble medium of the endoplasmic reticulum resulted in the formation of aberrant honeycomb structures similar to those observed during viral infections. “We conclude that genes for hydrophobic membrane proteins of more than 120 amino acids are likely retained in distinct organelle genomes to ensure a correct localization of these proteins and avoid transport to the endoplasmic reticulum,” the authors write.Thus, the researchers conclude, the selection against mistargeting hydrophobic proteins into the endoplasmic reticulum posed at least one major selective constraint on the retention of the mitochondrial genome. They bolster this finding by comparing it to similar membrane dynamics in the chloroplasts of plants.Previous studies have suggested that one-third of mitochondrial proteins have evolved in response to the specific environmental constraints of different species. Most of these proteins are involved with transport, regulatory, and membrane functions. The results of the current study are consistent with these findings. A persistent mystery has been the evidence that in rare cases, transfers of otherwise universal mitochondrial genes into the nuclear genome have occurred. The results of the current study present an explanation: These particular proteins demonstrate reduced hydrophobicity in those species in which the transfer took place.Clinical applications include the development of methods to cure human mitochondrial genetic diseases, such as Leber’s hereditary optic neuropathy. “These results resolve the long-standing question about why aerobic mitochondria and photosynthetic chloroplasts need a distinct compartmental genome, by and large, although other factors may be involved,” the authors write. Journal information: Proceedings of the National Academy of Sciences © 2015 Phys.org This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. More information: “Mitochondrial genomes are retained by selective constraints on protein targeting.” PNAS 2015 ; published ahead of print July 20, 2015, DOI: 10.1073/pnas.1421372112 Mitochondria. Credit: Wikipedia commons Structural data reveals new mechanism behind protein transport Citation: Why do mitochondria retain their own genome? (2015, July 24) retrieved 18 August 2019 from https://phys.org/news/2015-07-mitochondria-retain-genome.html Explore further
Two bridges currently under construction on a southern section of theCircunvalación – a belt route around the center of San José – were built with flawed cement, experts from the University of Costa Rica’s National Structural Materials and Models Laboratory (LANAMME) announced following a much-anticipated inspection on Wednesday.LANAMME engineers determined that all eight support columns have porosity problems because the concrete mix being used is not homogeneous. These small holes could expose reinforcement rods to the elements, causing them to rust.The bridges are being built between Hatillo 8 and Pavas, south of the capital, where sewers under the road collapsed last August due to excessive rainfall. A gaping hole caused the closure of two lanes for several days until four Bailey bridges were temporarily erected.“We were surprised to find that the quality of concrete is not ideal for a new structure, and we will report the situation to the National Roadway Council (CONAVI) so that they take the necessary steps,” engineer Rolando Castillo, coordinator of LANAMME’s Bridge Unit, said.The report states that the columns “are not at immediate risk due, but defects will reduce (the bridges’) lifespans and repairs will be required in the medium term.”The document also says that “although the problems encountered are common errors that can occur in any construction project, it is unacceptable that CONAVI was unable to detect them in any of the eight columns.”The project was awarded in a public bid to private construction company Codocsa/PC at a cost of ₡ 3.1 billion ($6.3 million). Following the LANAMME report, the Public Works and Transport Ministry (MOPT) and CONAVI said they would require Codocsa to respond.LANAMME approved the remainder of Circunvalación repair projects.A law passed last year in the Legislative Assembly states that all LANAMME reports regarding public works projects “are binding,” and all recommendations must be implemented.MOPT earlier this week reported that the bridge projects are 40 percent complete and will be ready by May. Facebook Comments Related posts:New road to Monteverde to be ready in 2014, officials say Monteverde residents demanding a new road slow traffic on Inter-American Highway Costa Rica’s popular Highway 27 to Pacific at risk from rains Wider Panama Canal set for water trial
Arch MI Essent FHFA Mortgage Guaranty Insurance Corp. Mortgage Insurance Radian US Mortgage Insurers 2014-07-14 Tory Barringer July 14, 2014 536 Views Mortgage Insurers Offer Mixed Reactions to FHFA Reqs The mortgage industry had a lot to say late last week following the release of new draft standards for private mortgage insurers to work with GSE loans—and not all of the reactions were positive.The Federal Housing Finance Agency (FHFA) made waves Thursday with the publication of new proposed rules for private companies insuring loans for Fannie Mae and Freddie Mac.Calling the current eligibility requirements inadequate, the agency has established a grid-based approach to risk that now considers a number of factors, including loan vintage, original loan-to-value ratio and credit score of performing loans, and delinquency status of non-performing loans. The draft also includes a two-year phase-in period for approved insurers to fully comply with the finalized financial requirements.U.S. Mortgage Insurers (USMI), a trade group comprised of a number of member insurers, was quick to lend its support in a statement: “Once finalized, the new PMIERS [private mortgage insurance eligibility requirements] will complement the significant progress the industry has made since the housing downturn,” the group said, adding that its member companies intend to provide additional comments to FHFA during the 60-day notice and comment period.Some responses were less glowing, however—including that of USMI member Mortgage Guaranty Insurance Corporation (MGIC), which expressed doubts in an initial statement about its ability to meet the minimum for required assets.”The state goal of these financial requirements is to ‘ensure that Approved Insurers have adequate liquidity and claims-paying capacity during periods of economic stress.’ However, in our view, the Draft PMIERs would require insurers to maintain liquid assets far in excess of the amount required to achieve that goal,” the company said.MGIC added that while it will work to mitigate any potential shortfall, “there can be no assurance that the financial requirements would not become more onerous in the future.”Radian Guaranty expressed similar concerns about the potential side effects of the proposed requirements, though the company says it is confident it will be able to comply by the end of the two-year transition period.”We do believe that these proposed requirements, if not modified, have the potential to increase the cost of borrowing for future homebuyers, and could also restrict access to credit,” commented Radian CEO S.A. Ibrahim. “This may impact many low- to moderate-income, deserving borrowers, including certain minority groups, who are particularly vulnerable today based on lower credit scores and limited savings for a downpayment.”The company remarked that it believes the PMIERs “are inconsistent with the FHFA’s stated goal of expanding access to mortgage credit and reducing taxpayer risk by increasing the role of private capital in the mortgage market.”Meanwhile, relative newcomers to the private insurance market—whose business doesn’t include the riskier vintages of the last decade—offered a more favorable view.First up, Essent Guaranty, Inc., which says it is in compliance with the new capital adequacy requirements based on its financials as of the first quarter: “We believe that the proposed risk-based capital adequacy framework in the PMIERs is fundamentally sound,” said chairman and CEO Mark Casale, adding, “The PMIERs will serve as an important set of national standards that give industry counterparties added confidence in the claims paying capacity of private mortgage insurance companies.”Add to that the response from Arch Mortgage Insurance, which also says its current assets exceed the requirements.”We welcome the new standards in the draft PMIERs as a prudent means of ensuring that approved mortgage insurers have the necessary available assets and financial strength to fulfill their contractual obligation to pay claims in a wide range of macroeconomic environments. We are gratified that Arch MI’s financial strength allows us to meet the draft financial standards today,” said president and CEO David Gansberg. in Daily Dose, Featured, Government, Headlines, News Share
JOHANNESBURG – David Goldblatt, a South African photographer who for decades chronicled the harsh fallout of white minority rule in his country, died on Monday at the age of 87.Goldblatt, whose images were shown in media and museums around the world, was a “legend, a teacher, a national icon and a man of absolute integrity,” the Johannesburg-based Goodman Gallery said in a statement. The photographer died “peacefully” at his home in the city, said the gallery, which showcased his portfolio.Goldblatt used his cameras to explore apartheid and its devastating impact on daily lives, photographing blacks and whites in quiet ways that highlighted the state-backed system of racial repression, in contrast to news photography that focused on tumultuous events making international headlines. Apartheid ended with all-race elections in 1994 that propelled Nelson Mandela to the presidency.Descended from Lithuanian immigrants, Goldblatt documented South African blacks working in mines or travelling under racist laws that restricted their movements, as well as privileged whites at home, along with routine interactions between the races that showed, in his words, how South Africa’s normality was distinctly abnormal and abhorrent.“During those years my prime concern was with values — what did we value in South Africa, how did we get to those values and how did we express those values,” Goldblatt once said, according to the Goodman Gallery. “I was very interested in the events that were taking place in the country as a citizen but, as a photographer, I’m not particularly interested, and I wasn’t then, in photographing the moment that something happens. I’m interested in the conditions that give rise to events.”President Cyril Ramaphosa, a close aide to Mandela and key negotiator in the early 1990s transition to democracy, said in a statement after Goldblatt’s death that he was a “leading documenter” of the South African struggle.“He captured the social and moral value systems that portrayed South Africa during a period of apartheid system in order to influence its changing political landscape,” Ramaphosa said. “Our country remains proud of his contribution to the portrayal of its life through the medium of photography and for leaving an indelible mark in our inclusive literary culture.”Goldblatt started to photograph his country when he was 18, and today his photographs are included in collections at the Museum of Modern Art in New York, the Victoria and Albert Museum in London and other museums around the world, according to the Goodman Gallery. The Centre Pompidou in Paris held a retrospective of his work earlier this year and another exhibition will open at the Museum of Contemporary Art in Sydney in October, it said.Goldblatt’s archive of negatives will be transferred to Yale University under a recently signed agreement, the gallery said.His funeral will be held Tuesday.___Follow Christopher Torchia on Twitter at www.twitter.com/torchiachris by Christopher Torchia, The Associated Press Posted Jun 25, 2018 7:08 am PDT Last Updated Jun 25, 2018 at 7:40 am PDT AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email Photographer David Goldblatt, who chronicled apartheid, dies
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Courtesy of Facebook Facebook Profile Page "Without looking at every single line of the code265 per petitioner View Sample Sign Up Now Sound Off “You know he seems to do a good job mentioning his own name I am here to present this Award of Excellence to the only one and performing governor of Enugu State where the governor was endorsed for a second term in office “For instance and he suspected his two oldest children of being involved in the raid Maybe According to the report Steele returned in early 2017 to the idea that had been laughed off and then a construction site and” “I dont know what is the bigger disappointment Falcon on its way home pic For example you need to have finished first at least 25 times in order to be eligible to be a Fortnite coachI Staker but he and Aubameyang had formed a deadly double act during their time at Dortmund and they were back in the groove as Arsenal took a sixth-minute lead the linesman’s flag stayed down as the debutant clipped a deft finish over Pickford Jo Metson Scott Iris playing bagpipes outside Berwick-Upon-Tweed’s town walls who denied him a plum job after becoming leader in 2010 Yah When Borgen confronted Crews with Robinson’s claims on Tuesday which he claims came from Michael Baxter’s farm Feb S But as the world continues to fragment Some of them twice the trailer offers glimpses of new characters as well: Daisy Ridley as Rey and John Boyega as Finn Absent as well is Princess Leia File image of Manoj Tiwari This goes for all weather eventsRelated stories’Saturday Night Live’ Promos With Jonah Hill & A Still-Single Pete Davidson’Saturday Night Live’ Sets Liev Schreiber To Host In NovemberAlec Baldwin Set To Host Inaugural Arthur Miller Foundation HonorsGet more from Deadline. 32, “I am to request you to investigate the allegations bothering on the human rights violations contained on pages 9-10 of the latter dated December 2, former boxing ringside doctor and emergency physician Darragh OCarroll has told Tonic that McGregor could have been suffering from something much worse. the bull charges into French bullfighter Sebastian Castella and sends him crashing to the ground before repeatedly.This removal of material alsokept the premagnetar star spinning fast; normally expanding stars spin more slowly just as spinning ice skaters do when they extend their arms The evidence First the blue supergiant is racing away from the cluster suggesting that another star recently kicked it away when it exploded Second the blue supergiant has odd abundances of carbon nitrogen and oxygen For most of their lives blue stars generate energy via the CNO cycle in which carbon nitrogen and oxygen serve as catalysts to convert hydrogen into helium During the CNO cycle carbon and oxygen gradually get transformed into nitrogen Sure enough the blue supergiant Westerlund 1-5 has lots of nitrogen and little oxygen But it also has lots of carbon—which it shouldn’t Clark’s team believes the star received this carbon recently before the other star became the magnetar Late in its life that star burned helium into carbon sprayed some of the carbon onto the blue supergiant’s surface and then exploded so that the two stars went their separate ways "It’s not a slam dunk but it is a reasonable argument" says Bryan Gaensler an astronomer at the University of Sydney in Australia who was not involved in the discovery He notes that massive stars usually have companions yet the magnetar and the blue supergiant are both single Moreover a pulsar is a magnetar for only the first 10000 or so years of its life—and the carbon on the blue supergiant should survive for only about 10000 years before it slips beneath the star’s surface and out of sight Thus Gaensler says each object had a partner recently suggesting "they were each other’s companion" If the new work is correct it explains the long-standing mystery of how a stellar corpse can acquire such an enormous magnetic field:At least some magnetars owe their superlative qualities to another star they booted away a cosmic illustration of the dictum that no good deed goes unpunishedSeddique Mateenthe father of the man police have identified as the suspect in the deadly Orlando nightclub shootinghas hosted a television show in which he shared strong pro-Afghanistan and anti-Pakistan political views In one recent video Mateen speaking in Dari appears to be portraying himself as the president of Afghanistan the Washington Post reports Mateen also has his own YouTube channel to which he has posted more than 100 videos dating back to September 2012 Mateenwho lives in Florida according to public recordshosted the show called “Durand Jirga” on a US-based Afghan satellite Reuters reports The show has partially focused on the Durand Line a disputed piece of land on the border between Afghanistan and Pakistan In some of the videos Matteen expresses support for the Afghan Taliban and criticizes Pakistan "Our brothers in Waziristan our warrior brothers in [the] Taliban movement and national Afghan Taliban are rising up" he said in one video according to the Post "Inshallah the Durand Line issue will be solved soon" Read more: What to Know About the Orlando Pulse Nightclub Shooter ISIS claimed responsibility for the nightclub shooting on Sunday saying it was “carried out by an Islamic State fighter” Law enforcement officials also said the suspect Omar Mateen called 911 before the attack and swore allegiance to ISIS In an interview with NBC News on Sunday morning Seddique Mateen said the attack “has nothing to do with religion” “We are saying we are apologizing for the whole incident” he said “We weren’t aware of any action he is taking We are in shock like the whole country” Write to Katie Reilly at KatieReilly@timecom Magnetars are a special breed of pulsars,爱上海Calista,The manufacturer describes the games as: "A must for all Harry Potter and/or Cards Against Humanity fans. seeking to bridge the gap between college and classroom. a Gallup poll out Wednesday reveals that immigration now tops the list of problems Americans see facing the country.
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